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KMID : 0370219870310010001
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Yakhak Hoeji
1987 Volume.31 No. 1 p.1 ~ p.9
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Synthesis of Angiotensin Converting Enzyme Inhibitors(II)
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윤혜숙/Yun HS
이종란/이희주/윤성미/이선/Lee JR/Lee HJ/Yun SM/Lee S
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Abstract
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The preparation of substituted benzoylamino acids and mercaptoacylamino acids as inhibitors of angiotensin converting enzyme is described. The bulky phenyl ring directly attacted to an amino acid as of benzoylamino acid seemed unsuitable for the inhibitory activities. Among the mercaptosuccinylamino acids, L-proline was more favorable than L-phenylalanine while S-acetylation was unfavorable.
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